Gainers

  • RH RHshares gained 22.48 percent to close at $92.24 on Wednesday after the company reported better-than-expected earnings for its fourth quarter and issued strong FY2018 earnings guidance.
  • Argan, Inc. AGXgained 17.28 percent to close at $44.80. Argan disclosed that its wholly-owned subsidiary Gemma Power Systems has finalized an EPC contract for 475 MW power project in North Carolina. Lake Street upgraded Argan from Hold to Buy.
  • Homology Medicines, Inc. FIXXclimbed 16.63 percent to close at $18.66. Homology Medicines priced its IPO at $16 per share.
  • RSP Permian, Inc.RSPP surged 15.62 percent to close at $45.00. Concho Resources Inc. CXO announced plans to buy RSP Permian in an all-stock deal.
  • LaSalle Hotel PropertiesLHO climbed 15.53 percent to close at $28.13. Pebblebrook Hotel Trust offered to buy LaSalle Hotel Properties in an all-stock transaction.
  • ITUS Corporation ITUSshares gained 13.13 percent to close at $3.79.
  • Sears Hometown and Outlet Stores, Inc. SHOSsurged 12.73 percent to close at $3.10 on Wednesday.
  • Quorum Health CorporationQHC rose 12.48 percent to close at $9.37.
  • Sears Holdings CorporationSHLD shares gained 12.4 percent to close at $2.81
  • Shire plc SHPGrose 12.15 percent to close at $144.53 after the Ireland-based pharmaceutical giant was named as an acquisition target by The Wall Street Journal. According to a report, Japan-based Takeda Pharmaceutical is in “preliminary and exploratory” talks to acquire Shire but no financial details of a transaction are known.
  • Lilis Energy, Inc. LLEXshares gained 11.36 percent to close at $3.92.
  • UniFirst CorporationUNF surged 10.18 percent to close at $159.65 following upbeat quarterly earnings.
  • Francesca’s Holdings CorporationFRAN gained 9.59 percent to close at $5.03 on Wednesday.
  • Lululemon Athletica Inc.LULU rose 9.21 percent to close at $85.96 in pre-market trading after the company posted upbeat earnings for its fourth quarter. The athletic apparel brand also issued strong first quarter and FY2018 guidance.
  • Kratos Defense & Security Solutions, Inc. KTOSgained 8.69 percent to close at $10.38.
  • Euro Tech Holdings Company Limited CLWTshares gained 8.08 percent to close at $2.81 on Wednesday after the company disclosed that it has signed an Equity Transfer Agreement to sell its 20 percent equity stake of Zhejiang Jiahuan Electronics Co., Ltd.
  • CGG CGGgained 6.36 percent to close at $2.08. Goldman Sachs upgraded CGG from Sell to Buy.
  • Tandem Diabetes Care, Inc. TNDMrose 5.54 percent to close at $4.76 after climbing 9.20 percent on Tuesday. Cowen & Co. upgraded Tandem Diabetes Care from Market Perform to Outperform.
  • Aqua Metals, Inc.AQMS rose 5.06 percent to close at $2.49. Aqua Metals announced plans to transition Dr. Stephen Clarke from his current position as President, CEO and Chairman of the Board.
  • Plantronics, Inc. PLTgained 4.7 percent to close at $57.45 as the company announced plans to acquire Polycom for $2 billion.

Losers

  • Edge Therapeutics, Inc.EDGE shares tumbled 91.6 percent to close at $1.31 on Wednesday after the company disclosed that its Phase 3 Newton 2 study is unlikely to achieve primary efficacy endpoint. The independent Data Monitoring Committee has recommended discontinuation of study.
  • InspireMD, Inc.NSPR declined 43.75 percent to close at $1.35. InspireMD priced its 2.857 million share offering at $1.75 per share.
  • Sorrento Therapeutics, Inc. SRNEshares dipped 26.98 percent to close at $4.60.
  • Zosano Pharma Corporation ZSANshares dipped 24.46 percent to close at $9.17 on Wednesday after tumbling 16.56 percent on Tuesday.
  • Flex Pharma, Inc. FLKSshares declined 23.77 percent to close at $5.13 on Wednesday.
  • Geron Corporation GERNdeclined 17.86 percent to close at $4.23 on Wednesday after dipping 13.88 percent on Tuesday.
  • Top Ships Inc. TOPSshares fell 17.86 percent to close at $2.07.
  • Innovate Biopharmaceuticals, Inc. INNTdropped 15.74 percent to close at $24.35.
  • Pareteum Corporation TEUMshares fell 15.58 percent to close at $2.60 after reporting a fourth quarter earnings miss. Earnings came in at a loss of 31 cents per share, missing estimates by 23 cents. Sales beat estimates by $235,000, coming in at $4.01 million.
  • Zion Oil & Gas, Inc. ZNslipped 15.57 percent to close at $3.96.
  • PTC Therapeutics, Inc. PTCTdropped 15.29 percent to close at $27.04 after announcing a proposed offering of common stock.
  • Arcadia Biosciences, Inc. RKDAdeclined 14.56 percent to close at $22.65.
  • Aptose Biosciences Inc. APTOshares fell 14.16 percent to close at $2.85. Aptose Biosciences reported a Q4 loss of $0.12 per share and announced a new at-the-market offering.
  • Invitae Corporation NVTAdeclined 13.12 percent to close at $4.70. Invitae priced its 11.11 million share offering at $4.50 per share.
  • Tintri, Inc. TNTRshares fell 11.59 percent to close at $1.83.
  • Roadrunner Transportation Systems, Inc. RRTSdeclined 11.49 percent to close at $2.62 on Wednesday.
  • Dicerna Pharmaceuticals, Inc. DRNAshares fell 11 percent to close at $8.90.
  • QuinStreet, Inc. QNSTshares tumbled 8.72 percent to close at $12.66.
  • Cerecor Inc. CERCshares fell 7.78 percent to close at $3.91. Cerecor named Peter Greenleaf as its CEO.
  • Shoe Carnival, Inc SCVLshares fell 5.14 percent to close at $24.20. Shoe Carnival reported upbeat earnings for its fourth quarter, while sales missed estimates. Comps were down 0.5 percent in the quarter.